Very little is known about Huber's life and artistic training. Around 1502 he produced his first imaginary landscapes and topographically identifiable landscape depictions with religious scenes under the influence of the early works of Lucas Cranach. Huber settled in Passau, where he established his workshop. In 1515 he was commissioned to create his most important work, the 'St Anne Altar' for his home town of Feldkirch. From that year on, Huber also worked as court artist and architect for the prince-bishops of Passau, a position he held until his death in 1553. More than is the case with other artists of his generation, drawing forms the core of his work as an independent genre. Along with Albrecht Altdorfer, Huber is considered one of the most important representatives of the Danube School, with a major influence on the landscape painting of the following period.